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Niacinamide Explained:
How Does It Work on Your Skin?

Niacinamide is a form of vitamin B3 studied for the skin barrier and tone appearance. A serum's percentage alone does not tell you how effective or well tolerated it will be.

Klaris EditorialUpdated: 6 Min Read
In This Article

Niacinamide is the form of vitamin B3 (nicotinamide) used in cosmetic formulations. It appears on the label as Niacinamide. It is water-soluble, stable across a broad pH range and easy to formulate in many product types, which is why it often appears in toners, serums, moisturisers and masks.

What Does It Do for the Skin?

Niacinamide is associated with several roles in cosmetic literature. The most frequently highlighted areas are:

  • Barrier: Tanno and colleagues reported increased ceramide and free fatty acid levels and reduced water loss after topical niacinamide use on dry skin. This helps explain support for the barrier that retains moisture.
  • Tone appearance: Hakozaki and colleagues reported reduced dark-spot appearance compared with the control formula after four weeks in their clinical studies.
  • Redness appearance: Bissett and colleagues studied a 5% niacinamide formula for 12 weeks in 50 women with facial photoaging. They reported improvements in the appearance of red blotchiness and dark spots.

These findings explain why niacinamide products are used for barrier and tone goals. Results apply to the formulas and groups studied; cosmetic research on redness appearance is distinct from rosacea treatment.

Measured Doses: Why Do They Matter?

Hakozaki and colleagues evaluated different formulas containing 2% and 5% niacinamide. These are not universally recommended doses or a direct comparison between the two percentages.

In practice, read the percentage alongside texture, other ingredients and product directions. Instead of automatically equating a higher concentration with better results, focus on your goal and a formula you can comfortably use.

Which Profiles May It Suit?

Niacinamide may be chosen for a relatively broad range of profiles, although every skin can react differently. General tendencies include:

  • Sensitive skin: Even a low percentage does not guarantee tolerance; the formula's other ingredients matter too.
  • Oily or combination skin: Stands out as an active often recommended in lightweight formulas.
  • Dry skin: Included in barrier-friendly formulas as a compound that supports moisture retention.
  • Mature skin profiles: Often found in formulas that contribute to a more even-looking tone.

Notes on Combined Use

If you also use vitamin C, consider both products' directions and the routine as a whole. A finished formula and mixing separate serums are different situations. Explore formula and goal differences in the vitamin C or niacinamide comparison.

If you are new to actives, adding one at a time makes it easier to identify the source of any reaction.

This article is for information only; it does not provide a medical diagnosis, treatment or a guarantee of safety. If you have sensitivities, are pregnant or have particular circumstances, you are advised to discuss your decisions with your own doctor.

Source Basis

Related ingredient guides are listed below. You can review the source links in each guide and consider their scope separately.

Authoritative Starting Points

Search and institutional links are starting points for research; they do not, on their own, verify every statement in the article. For the assessment framework, see our methodology document.

See It in Context

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